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Takeshi Kitamura, MD; Takashi Kanda, MD; Takeru Ishikawa, MD; Takashi Shimizu, MD

Arch Otolaryngol. 1970;91(1):64-70.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE Sjögren syndrome is an autoimmune disease¹ which occurs most commonly in middle-age women. Sjögren's syndrome is characterized by keratoconjunctivitis sicca, arthritis, and dry mouth with or without enlargement of the parotid gland. A number of cases have been reported since Sjögren published his monograph in 1933,² and a number of the clinical manifestations have been added.^3-6 Steroid hormone therapy is the most effective upon the recurrent swelling of the parotid gland and keratoconjunctivitis sicca. This syndrome is not fatal, commonly. Few patients of this disease, however, also have rheumatoid cardiac disease or systemic lupus erythematosus which leads to death. Histological changes of the parotid gland are characterized by atrophy of acini and ducts, and by infiltration of lymphocytes, plasma cells, and eosinophils.⁷ In order to establish the definite diagnosis of this syndrome, in an early stage, biopsy of the parotid gland and the immunoserological reactions found . . . [Full Text PDF of this Article]

Author Affiliations
Chiba City, Chiba, Japan

From the Department of Otolaryngology, Chiba University School of Medicine, Chiba, Japan. Dr. Ishikawa is currently at the Allergy Research Laboratory, Buffalo General Hospital, Buffalo, NY.

Footnotes
Accepted for publication April 8, 1969.

Reprint requests to Department of Otolaryngology, Chiba University School of Medicine, 313 Inohana cho, Chiba City, Chiba, Japan (Dr. Kitamura).

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