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Clarence T. Sasaki, MD

Arch Otolaryngol. 1968;87(4):396-399.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DISTANT visceral metastasis occurs relatively infrequently in squamous cell carcinoma of the head and neck. Local involvement rather than spread below the clavicles is in part explained by the role of cervical lymphatics as temporary barriers between the primary tumor and the rest of the body. Distant spread therefore has in the past been viewed as blood-borne metastasis. However, search of the available literature yields several articles dealing with the problems of cervicomediastinal tumor extension, the suggested rationale for which lies in the anatomic communications between the cervical and mediastinal lymphatics at the base of the neck. The possibility of a purely lymphatic route is anatomically reasonable and finds additional support by recent in vivo dye-injection studies of cervical lymphatics following subclavian vein ligation in rabbits and cats.¹

A case of far-advanced nasopharyngeal carcinoma is reported which demonstrates cervicomediastinal extension of tumor with invasion of the pulmonary hilar parenchyma. . . . [Full Text PDF of this Article]

Author Affiliations
San Francisco

From the Otolaryngology Service, San Francisco General Hospital, University of California Medical Center, San Francisco. Dr. Sasaki is now at Dartmouth Medical Center, Mary Hitchcock Memorial Hospital, Hanover, NH.

Footnotes
Accepted for publication Nov 14, 1967.

Reprint requests to Dartmouth Medical Center, Mary Hitchcock Memorial Hospital, Hanover, NH (Dr. Sasaki).

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