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Hereditary Hemorrhagic TelangiectasiaReview of 102 Cases and Presentation of an Innovation to Septodermoplasty
CAPT RAYMOND H. STECKER, MD;
CLIFFORD F. LAKE, MD
Arch Otolaryngol. 1965;82(5):522-526.
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SINCE 1865 when Babington1 first called attention to this unusual form of epistaxis in a brief letter to the editor of Lancet, physicians have written on the history, etiology, pathology, clinical syndrome, and treatment of hereditary hemorrhagic telangiectasia. Rendu2 was the first to associate telangiectasia with familial epistaxis and separate it from hereditary hemophilias. Osler3 in 1901 gave the first complete clinical description of the disease, pointing out the familial occurrence and the total body distribution of hemorrhagic telangiectasia. Six years later Weber discussed the condition, and he later emphasized that this was a "congenital-developmental" disease which manifests itself in later life.4
In 1909 Hanes,5 the forgotten man in Rendu-Osler-Weber disease, was the first to give the histopathologic description of the lesion and produce color plates of persons with typical lesions. His classic description of the skin lesions of hereditary hemorrhagic telangiectasia spoke of "the
. . . [Full Text PDF of this Article]
Author Affiliations
USAF; ROCHESTER, MINN
From the Mayo Clinic and Mayo Foundation, Section of Otolaryngology (Dr. Lake), and the Mayo Graduate School of Medicine, University of Minnesota (Dr. Stecker).
Footnotes
Submitted for publication June 21, 1965.
The contents of this article are the personal views of the Air Force officer and are not to be construed as a statement of official Air Force policy nor as Air Force endorsement of any commercial product described.
Reprint requests to Mayo Clinic, Rochester, Minn 55902.
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