This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

An Experimental Study in Dogs

S. DONALD GREENBERG, M.D.; RICHARD K. WILLMS, M.D.

Arch Otolaryngol. 1962;75(4):335-341.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Extensive experimental and clinical investigations which we recently reviewed¹ failed to produce a satisfactory tracheal replacement. This study was made to evaluate tracheal prostheses composed of 3 different types of materials for "sleeve" reconstruction of the trachea and to observe regeneration of the respiratory epithelium. Furthermore, since continuous movement of the mucus in the tracheobronchial tree by the ciliated respiratory epithelium is of prime importance in cleansing the air passages, in vitro studies were made using graphite particles to evaluate the function of the regenerated epithelium.

Method

We selected 21 large dogs weighing 12 kg. or more because the diameter of their tracheas approximates that of man. The operations were performed under intravenous anesthesia, using pentobarbital (Nembutal), 30 mg. per kilogram.

Group 1.—In eleven dogs, celiotomy was performed, and a portion of polyethylene plastic (Marlex) mesh, 6x6 cm., was sutured into the greater omentum. The Marlex mesh was removed . . . [Full Text PDF of this Article]

Author Affiliations
HOUSTON, TEXAS

From the Department of Pathology and the Cora and Webb Mading Department of Surgery, Baylor University College of Medicine, and the Veterans Administration Hospital.

Footnotes
Submitted for publication Nov. 9, 1961.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?