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Effects of X-Ray on the Tympanal Mesenchyme CycleExperiments on the White Rat
PAUL GUGGENHEIM, M.D.;
LEO CLEMENTS, Ph.D.;
ALLEN SCHLESINGER, Ph.D.;
PATRICK PEARTREE, M.D.;
WILLIAM JURGENSEN, M.D.;
RAYMOND McDONALD, M.D.
Arch Otolaryngol. 1961;74(2):185-188.
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The effects of ionizing radiation upon unresorbed embryonic mesenchyme in the middle ear have not been hitherto reported. In view of the use of x-ray as a treatment modality in certain pediatric otologic problems, such knowledge is desirable. The deleterious effect of mesenchyme upon the incidence and outcome of otitis media (including hearing) has been appreciated for some time.
Wolff,1 Guggenheim,2 and Wilson3 have all emphasized the vicious cycle of cause and effect between persistent mesenchyme and otitis media and its sequelae. Their studies added a new chapter to the older interest in mesenchyme, dating from Wittmaack, which
. . . [Full Text PDF of this Article]
Author Affiliations
COUNCIL BLUFFS. IOWA
From the Departments of Otolaryngology, Microanatomy, and Radiology, Creighton University School of Medicine. This research is being conducted under a grant from the National Institute of Health.
Footnotes
Submitted for publication Jan. 24, 1961.
Professor Emeritus of Histology (Dr. Clements); Professor of Biology (Dr. Schlesinger); Department of Radiology (Drs. Peartree, Jurgensen, and McDonald).
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