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A Critical Study of a New Cerumenolytic Agent
ARTHUR C. REINIGER, M.D.;
GEORGE BIALKIN, M.D.;
JAMES Q. GANT, M.D.;
MANNING J. ROSNICK, M.D.;
ANTHONY J. MONTEBOVI, M.S.;
ALFRED HALPERN, Ph.D.
AMA Arch Otolaryngol. 1959;69(3):293-302.
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The medical literature contains many references1-5 to the dangers of excessive or impacted cerumen, yet there is little to offer pharmaceutically to either physician or patient for its safe, convenient, and effective removal. Many of the preparations recommended for this purpose have been abandoned when it was found that they were not effective for the intended purpose, or, in some instances, introduced secondary problems which interfered with their efficacy. This report describes the development and study of a new cerumenolytic which has been found to be a safe and effective agent for the removal of excessive or impacted cerumen.
In 1947, Senturia and associates6 reported that many formulations which claimed to be efficient cerumenolytic agents were, in effect, worthless. According to this group's findings, irrigation with distilled water and hydrogen peroxide remained the best means of disintegrating ear wax. However, since 1947, there have been many advances made
. . . [Full Text PDF of this Article]
Author Affiliations
New York; Washington, D. C.; Coral Gables, Fla.; Brooklyn; New York
Chief, Department of Otolaryngology, The Stuyvesant Polyclinic, Lecturer, New York Polyclinic Medical School, N. Y. (Dr. Reiniger); Adjunct Pediatrician, Bronx Hospital (Dr. Bialkin); Assistant Professor of Dermatology, George Washington University, and Chief, Department of Dermatology, V. A. Regional Office (Dr. Gant); Active Attending, Department of Medicine, University of Miami School of Medicine (Dr. Rosnick); Professor, Department of Chemistry, College of Pharmacy, St. John's University (Mr. MonteBovi); Director, Department of Experimental Therapy, The Stuyvesant Polyclinic (Dr. Halpern).
Footnotes
Submitted for publication June 2, 1958.
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