This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Preliminary Report of Sixty-Six Patients Treated with Promethazine

DON J. WEEKES, M.D.

AMA Arch Otolaryngol. 1958;68(6):748-751.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Nasal allergy as a complicating and often confusing accompaniment to diseases of the upper respiratory system has been frequently reported in medical literature. Silbert,¹ in stressing the necessity for differential diagnosis of this syndrome, estimates that 75% of the patients he sees exhibit some form of sensitivity; and Gehrand,² in a clinical study of 134 cases selected for extreme susceptibility to respiratory infections, found well-defined clinical evidence of allergy in 74%.

Promethazine,* a potent and long-acting antihistamine, has proved effective in a wide variety of allergic upper respiratory disorders.^3-6 The therapeutic efficiency of this drug, combined with its freedom from undesirable side-effects, suggested a clinical evaluation of promethazine for symptomatic relief of secretory otitis media and nasal allergy concurrent with specific treatment of the underlying condition.

Method

The study comprised 66 patients (61 adults and 5 children) ranging in age from 8 to 73 years, who were . . . [Full Text PDF of this Article]

Author Affiliations
Boston

Footnotes
Submitted for publication Feb. 24, 1958.

Phenergan, promethazine hydrochloride, was supplied by Wyeth Laboratories.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?