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THOMAS F. FLYNN, Jr., M.D.

AMA Arch Otolaryngol. 1957;65(3):203-213.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The glucocorticoids recently have attained great acclaim in the armamentarium of the otolaryngologist. There is no doubt that they have their place as therapeutic agents in certain diseases with which we are concerned; however, the misuse of these hormones is wide-spread. I say this because these hormones are being utilized in the treatment of diseases in which the rational of their use is not justified. To understand the effect of the corticosteroids some basic concepts must be understood (Fig. 1).

As their name implies, these hormones emanate from the cortex of the adrenal gland, the latter being composed of several layers. It is believed that desoxycorticosterone (Doca) is produced in the granulosa layer and cortisone and hydrocortisone (Compound E and Compound F, respectively) in the zona fasciculata. Sex hormones, such as estrogens and androgens, emanate from the reticular layer and epinephrine, naturally, from the medulla. Of the 28 or . . . [Full Text PDF of this Article]

Author Affiliations
Woodbury, N. J.

Footnotes
Accepted for publication July 24, 1956.

Read before the Section on Otolaryngology at the 190th Annual Meeting of the Medical Society of New Jersey in Atlantic City, N. J., on May 16, 1956. This paper has been released for publication here through the courtesy of the Journal of the Medical Society of New Jersey.

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