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  Vol. 64 No. 4, October 1956 TABLE OF CONTENTS
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Intranasal Chondrosarcoma

A Supplemental Case Report

LAWRENCE J. LAWSON, M.D.

AMA Arch Otolaryngol. 1956;64(4):331-334.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Chondromas, from which chondrosarcomas originate, have a typical pattern with the following characteristics: 1. Their cells are arranged singly, not in groups; 2. They are not vascular; 3. They are liable to undergo myxomatous degeneration; 4. They grow slowly and exhibit histologic evidence of a high degree of differentiation; 5. They are capable of local invasion; 6. They tend to recur.

Chondrosarcomas exhibit these specific evidences of malignancy: 1. The intercellular matrix is poorly formed; 2. There is increased cellularity; 3. There are irregular nuclear patterns; 4. There is obvious accelerated growth at the margin of the lobules. The primary type, according to Coley,1 arises from relatively undifferentiated cells in the perichondrium. These cells give origin to tumors which usually occur in young persons, and a striking feature is the development of metastases and extensions into the veins. The secondary type, which is commoner, often arises from cartilage rests . . . [Full Text PDF of this Article]


Author Affiliations

Evanston, III.

From the Department of Otolaryngology (Associate Professor), Northwestern University Medical School, and the Evanston Hospital.


Footnotes

Accepted for publication April 6, 1956.

Read before the Chicago Laryngological and Otological Society April 2, 1956.



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