This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

N. EDWARD NACHLAS, M.D.

AMA Arch Otolaryngol. 1955;62(6):591-592.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Werlhof in 1735 was the first to describe a symptom complex of hemorrhagic purpura. The essential type of this disease is sometimes referred to as Werlhof's disease.

Thrombocytopenic purpura is characterized by multiple hemorrhages into the skin and mucous membranes. One of the earliest indications of hemorrhage may be epistaxis, and the otolaryngologist may be the first to suspect the diagnosis and be instrumental in the institution of early treatment.

Thrombocytopenic purpura is characterized by prolonged bleeding time, poor clot retraction, an increase in capillary fragility, and a decrease in circulating platelets. It may be classified as (1) the essential, or primary, type and (2) the symptomatic, or secondary, type. In 1946 Dameshek and Miller suggested that the essential type was due to a splenic factor acting to prevent the formation of platelets. The symptomatic type was found with hypoplastic bone marrow. This may be due to a nutritional . . . [Full Text PDF of this Article]

Author Affiliations
Baltimore

Footnotes
Accepted for publication Aug. 18, 1955.

Instructor in Otolaryngology, Johns Hopkins Medical School.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?