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The Rational Approach to Immunization of the upper Respiratory Tract
THEODORE E. WALSH, M.D.
AMA Arch Otolaryngol. 1955;62(6):569-572.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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That a virus is the etiologic agent in many of the infections of the upper respiratory tract has long been recognized. Kruse1 in 1914, Foster2 in 1917, and Dochez3 and his co-workers in 1930 demonstrated that a common cold could be induced in a human subject by the intranasal instillation of filtered washings from the nasopharynx of a subject with an acute cold.
Much work has been done in recent years in an effort further to elucidate the role of the virus in upper respiratory infections. In a recent review article Roden4 summarizes this work, and the results seem to indicate the following:
1. There are probably several of the viruses responsible for upper respiratory diseases.
2. These viruses are not pathogenic for animals other than man and the chimpanzee.
3. Infections can be transmitted in an experimental human subject in approximately 30% to 50% of
. . . [Full Text PDF of this Article]
Author Affiliations
St. Louis
From the Department of Otolaryngology, Washington University School of Medicine.
Footnotes
Recorded for publication Sept. 13, 1955.
Read before the Section on Laryngology, Otology and Rhinology at the 104th Annual Meeting of the American Medical Association, Atlantic City, June 9, 1955.
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