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AMYLOIDOSISReport of an Unusual Case
E. P. CARDWELL, M.D.;
WILLIAM G. BERNHARD, M.D.;
JOSE Aq. AQUINO, M.D.
AMA Arch Otolaryngol. 1955;62(5):528-531.
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AMYLOIDOSIS is a condition where there is deposition of a hyaline-like substance, apparently of protein nature but reacting like starch to iodine and sulfuric acid. It commonly involves the mesodermal tissues. It is seen grossly as a structureless translucent material which transmits the color of the underlying tissue and microscopically as a hyaline substance which accumulates between parenchymatous cells and in the connective tissue.
We are reporting a case because of the unusually localized tumor-like nodule found at the base of the tongue. This is in contrast to the usual diffuse nature of amyloidosis, which gives the tongue a uniform enlargement. There is difficulty in the differential diagnosis from other granuloma-like lesions.
Four varieties of amyloidosis are commonly recognized, according to the classification first proposed by Reimann, Koucky, and Eklund.1
1. Secondary amyloidosis is the commonest form and is associated with long-standing infections of destructive nature, such as tuberculosis
. . . [Full Text PDF of this Article]
Author Affiliations
Newark, N. J.
Footnotes
Submitted for publication Aug. 2, 1955.
Attending Otolaryngologist, Hospital of St. Barnabas and for Women and Children, Martland Medical Center, Newark Eye and Ear Infirmary (Dr. Cardwell). Director of Laboratory, Hospital of St. Barnabas and for Women and Children (Dr. Bernhard). Assistant Resident in Otolaryngology, Newark Eye and Ear Infirmary, Martland Medical Center (Dr. Aquino).
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