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Endobronchial Placer Mining for Neoplastic Cells
JOHN B. GREGG, M.D.;
BYRON M. MERKEL, M.D.;
KENNETH R. CROSS, M.D.
AMA Arch Otolaryngol. 1955;61(3):267-276.
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In recent years, with the advent of mass survey chest x-rays, the emphasis placed upon diagnosis of pulmonary pathology,* and the increasing incidence of neoplasm, the subject of lung cancer has received widespread attention. Fortunately, the primary effort has been directed toward early diagnosis and therapy because of the severity of this lesion. With the emphasis on case finding, the problem of demonstrating abnormal tissue for diagnosis prior to surgery has fallen upon the endoscopist. Unfortunately, in many early lung lesions, direct examination with the bronchoscope shows little or no evidence of neoplastic activity. In such cases biopsy becomes haphazard and of doubtful value.
It is in these cases that directed, excoriating aspirations of small tissue fragments and cell clumps have proved to be of great value. The diagnosis of lung neoplasms by bronchoscopic examination has showed disparity in positive results, varying from 30% to as high as 80%. Because
. . . [Full Text PDF of this Article]
Author Affiliations
Sioux Falls, S. D.; Des Moines, Iowa; Iowa City
From the Otolaryngology Section, U. S. V. A. Hospital, Iowa City, Iowa (Dr. Gregg). Attending in Otolaryngology, U. S. V. A. Hospital, Des Moines, Iowa (Dr. Merkel). From the Pathology Departments, U. S. V. A. Hospital and the College of Medicine, State University of Iowa, Iowa City, Iowa (Dr. Cross).
Footnotes
References 1 to 5.
References 6 to 26.
References 28 to 66.
References 12, 13, 69, and 70.
References 47, 62, and 71.
References 12, 13, 67, and 72.
References 73 to 75.
References 76 and 77.
References 78 and 79.
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