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JOHN R. AUSBAND, M.D.; JAMES A. HARRILL, M.D.

AMA Arch Otolaryngol. 1954;59(4):499-502.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A RECENT report has indicated that chloramphenicol (Chloromycetin) used locally is of value in the treatment of infected ears.¹ Ears draining because of many causes (acute and chronic external otitis, otitis media with central and marginal perforations of the tympanic membrane, and postoperative mastoid cavities) were treated with a 1.5% solution of chloramphenicol. The primary diluent of the drug was acetyl dimethylamine, secondarily diluted with 70% alcohol. The use of this drug resulted in cessation of drainage in 78% of the ears so treated.

Many other drugs have been similarly locally used for relief of drainage in diseased ears. Among these can be mentioned nitrofurazone (Furacin),* dihydrostreptomycin-boric acid powder,⁵ a sulfanilimide derivative (Sulfamylon), streptomycin,⁸ Sulfamylon and streptomycin,⁹ and polymyxin-bacitracin.¹⁰ Peele² refers to over 50 articles on various medications (not all different) used in treating draining ears, including many of those previously noted.

It is, . . . [Full Text PDF of this Article]

Author Affiliations
WINSTON-SALEM, N. C.

From the Department of Otolaryngology, Bowman Gray School of Medicine of Wake Forest College.

Footnotes
Chloramphenicol in this study was made available through the courtesy of Parke, Davis & Company, Detroit.

References 2 to 4.

References 6 and 7.

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