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ANTIRETICULAR CYTOTOXIC SERUM IN PEDIATRIC OTOLARYNGOLOGY
EDGAR I. STEINBERG, M.D.
Arch Otolaryngol. 1950;51(4):514-525.
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REPORTS1 from the Academy of Sciences of the Ukrainian Socialist Soviet Republic in 1942 on the effective therapeutic use of antireticular cytotoxic serum have presented it as a new agent for clinical use in many pathologic processes and, in particular, for such otolaryngologic conditions as atrophic rhinitis. Antireticular cytotoxic serum for use in man is produced by intravenous injection into animals of a saline extract of spleen and bone marrow taken after death from persons who had died from injury and who had had no acute or chronic disease. The tissues are obtained within ten hours after death from persons not more than 40 years old. The antiserum developed in animals is used in treating diseases in man in which it seems necessary to stimulate the trophic, plastic or protective functions of the physiologic system of the reticuloendothelial tissue. Mihailovsky, Smirnova and Marchuk2 reported the effects of antireticular cytotoxic
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
From the Department of Otolaryngology, Graduate Hospital of the University of Pennsylvania, and Children's Hospital of Philadelphia.
Footnotes
Abridgment of a thesis submitted to the faculty of the Graduate School of Medicine of the University of Pennsylvania in partial fulfilment of the requirements for the degree of Master of Medical Science [M. Sc. (Med.)] for graduate work in otolaryngology.
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