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A STUDY OF HYGROSCOPIC AGENTS

HOWARD C. BALLENGER, M.D.

Arch Otolaryngol. 1939;29(1):115-123.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The laboratory experiments of Mulinos and Osborne¹ on the conjunctivas of rabbits and the clinical investigation of Flinn² on the respiratory mucosa led to their conclusion that diethylene glycol is definitely less irritating than is glycerin when used as the hygroscopic agent in cigarets. Haag,³ at the Medical College of Virginia, in duplicating the work of Mulinos and Osborne failed to find any difference in irritation of the conjunctival sacs of rabbits as determined by the appearance of hyperemia, edema and blepharospasm and by the objection of the animal. Holck and Carlson,⁴ at the University of Chicago, failed to find difference in salivation in human beings subjected to the smoke of the two types of cigarets. From a clinical standpoint, Sharlit⁵ was unable to find any difference between the irritating properties of cigarets treated with glycerin and of those treated with diethylene glycol. In a clinical investigation in 1936.⁶ Johnson . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Otolaryngology, School of Medicine, Northwestern University.

Footnotes
Aided by a grant from the Glycerin Producers' Association.

Read at the Sixtieth Annual Congress of the American Laryngological Association, Atlantic City, N. J., June 4, 1938.

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