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JOSEPH L. GOLDMAN, M.D.; GREGORY SHWARTZMAN, M.D.; CECELE HERSCHBERGER, B.S

Arch Otolaryngol. 1935;21(2):154-156.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It is well known that the presence of Pneumococcus type III in acute mastoiditis offers a serious prognosis because of the frequency of subsequent intracranial complications. Inasmuch as these complications occur, as a rule, at least several weeks after the initial infection, attempts to induce a state of active acquired immunity should receive serious consideration. Prophylactic vaccination has been suggested by Kolmer and Amano¹ on the basis of their work with rabbits in which immunization with pneumococcus vaccines afforded protection against experimental meningitis. Barach² demonstrated that type-specific active immunity was acquired within six days after intradermal or intravenous injection of pneumococcus type-heterologous vaccines in cases of lobar pneumonia. Accordingly, in September 1931, a study was undertaken to determine the efficacy of immunization against intracranial infections in cases of mastoiditis due to infection with Pneumococcus type III. To accomplish this, every patient admitted to the otologic service of . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Laboratories and the Otological Service of the Mount Sinai Hospital.

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