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AGRANULOCYTOSIS (MALIGNANT NEUTROPENIA)
ROBERT F. RIDPATH, M.D.
Arch Otolaryngol. 1934;20(6):765-781.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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It is reasonable to believe that as man advances in civilization new diseases will arise in response to new environmental phenomena.
Most authorities agree that agranulocytosis, or malignant neutropenia, has not been described in past years because it is a comparatively recent disease. Although blood counts have been taken for more than fifty years in most hospitals, not one case of this condition was reported in these institutions.
A thorough review gives Senator1 the credit of the first report in the literature. In 1888, he reported four cases of an unusual type of pharyngitis, all resulting in death. The clinical picture closely followed malignant neutropenia. Pepper,2 in an excellent article on this subject, stated that Mackenzie3 gave Gubler,4 in 1857, and Trousseau,5 in 1865, credit for describing the symptomatology of this condition and differentiating it from other anginas, including diphtheria. It was, however, not until
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
Footnotes
Read before the Section on Laryngology, Otology and Rhinology at the Eighty-Fifth Annual Session of the American Medical Association, Cleveland, June 14, 1934.
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