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GEORGE M. COATES, M.D.; MATTHEW S. ERSNER, M.D.; DAVID MYERS, M.D.

Arch Otolaryngol. 1934;20(5):615-648.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since Gradenigo first described his classic triad, numerous authors have endeavored to offer explanations for this condition. Careful histologic study has added much to the knowledge of disturbances of the temporal bone.

It is known that at least 80 per cent of the patients with Gradenigo's syndrome recover following simple mastoidectomy. In the 20 per cent who succumb, histopathologic study reveals that suppuration of the apex of the petrous portion of the temporal bone is more frequent than has been suspected.

It has been argued by many that Gradenigo's syndrome is not a distinct clinical entity, owing to the lack of adequate anatomic and pathologic bases. Numerous attempts have been made to show that palsy of the sixth nerve is due to involvement in Dorello's canal (Vail¹ and others), to venous congestion (Freisner and Druss,² Ruskin,³ and others) or to localized meningeal irritation (Eagleton⁴).

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Author Affiliations
PHILADELPHIA

From the department of otology, School of Medicine, Temple University, and of the Graduate School of Medicine, University of Pennsylvania.

Footnotes
Read before the Section on Laryngology, Otology and Rhinology at the Eighty-Fifth Annual Session of the American Medical Association, Cleveland, June 14, 1934.

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