
Progress in OtolaryngologyA Summary of the Bibliographic Material Available in the Field of OtolaryngologyTUMORS OF THE NOSE AND THROAT
GORDON B. NEW, M.D.;
WALTER A. KIRCH, M.D.
Arch Otolaryngol. 1933;17(4):563-582.
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GENERAL CONSIDERATIONS
Englmann1 found that doses of roentgen rays or radium which were lethal for the tumor cells produced a marked reaction in the surrounding tissues. He considered the radiosensitivity of various types of tumors and the effects of irradiation on healthy tissues. He found that with the protracted fractional method far greater doses of radium or roentgen rays can be used without permanent injury to the normal tissues than with the old method of single doses, because the tissues maintained their regenerative powers.
Richter2 reported 115 cases encountered between 1919 and 1926. Twenty-two of the patients (19 per cent) had been well for five years or more at the time of the study. Eighty-five of the tumors were carcinomas and 25 were sarcomas. For operable conditions Richter advised a surgical procedure followed by irradiation, particularly in cases of carcinoma. Sarcoma is more susceptible to treatment by
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Author Affiliations
Fellow in Otolaryngology, the Mayo Foundation ROCHESTER, MINN.
From the Section on Laryngology and Oral and Plastic Surgery, the Mayo Clinic.
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