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THE SPECIFIC PROPHYLAXIS OF PNEUMOCOCCUS AND OF STREPTOCOCCUS MENINGITISII. VACCINE PROPHYLAXIS
JOHN A. KOLMER, M.D.;
K. W. AMANO, M.D.
Arch Otolaryngol. 1932;15(4):547-556.
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Fortunately while pneumococcus and streptococcus meningitis are uncommon complications of paranasal sinusitis, otitis media and mastoiditis, yet the dreadful mortality of these meningeal infections, despite newer methods of treatment,1 warrants serious consideration of the possible value of immunologic measures for their prevention.
In a previous communication 2 we have shown that pneumococcus meningitis of rabbits, especially that produced by type I pneumococcus, may be prevented by the administration of Felton's antipneumococcus serum. The results with types II and III pneumococci were less pronounced but not without some encouragement, as was likewise the prevention of streptococcus meningitis, produced with a hemolytic strain, by the administration of antistreptococcus serum with special reference to scarlet fever antitoxin.
On the basis of these results we advised the more frequent bacteriologic examination of the secretions in cases of paranasal sinusitis and mastoiditis before or during operation and the prompt administration
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
From the Research Institute of Cutaneous Medicine of Philadelphia. Aided by a grant from the Daniel J. McCarthy Fund for Research in Neurology of Temple University.
Footnotes
Submitted for publication, Nov. 30, 1931.
Thesis presented by Dr. K. W. Amano to the Faculty in Otolaryngology of the Graduate School of Medicine of the University of Pennsylvania in partial fulfilment of the requirements for the degree of Doctor of Medical Science.
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