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RICHARD SCHWARTZ, MD
Vienna, Va

Arch Otolaryngol Head Neck Surg. 1986;112(6):679.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—In the January 1986 issue of the ARCHIVES, Mattucci et al¹ report a study of the effectiveness of minocycline vs amoxicillin in the treatment of acute bacterial sinusitis. The dose of minocycline (Minocin) given to the adults was 100 mg twice a day, an appropriate dose. The dose of amoxicillin, however, was 250 mg three times a day, about the same as that given to a 4-year-old child. Since minocycline comes in a 50-mg capsule, the authors should have prescribed 50 mg of minocycline twice a day or, more appropriately, 500 mg of amoxicillin three times a day. Because of this underdose, the conclusions of the study seem suspect, at least to me. . . . [Full Text PDF of this Article]

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