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Injectable Liquid Silicone
RICHARD B. ARONSOHN, MD
Los Angeles
Arch Otolaryngol. 1985;111(1):70.
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To the Editor.—In the February issue of the ARCHIVES, Kamer and Churukian1 state that "the liquid silicone most often used for injection has been polydimethyl-siloxane polymer (Dow Corning 'Medical Grade 360'), a substance that was not intended for injection. Even in controlled settings, an unacceptable percentage of granulomas and other severe complications have been reported, sometimes years following injection."
When this substance was introduced in 1963, it was produced by a pharmaceutical house under the name "Medical Grade Silicone," with the label stating, "Dow Corning does not intend that this product be used as a 'drug' as defined by the Food Drug and Cosmetic Act. It is your responsibility to determine the status for your particular usage."
Physicians who obtained this liquid used it as an injectable implant material mainly to improve facial scars and to ameliorate some of the signs of aging of the face. Dow Corning
. . . [Full Text PDF of this Article]
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