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NOAH FOX, M.D.

Arch Otolaryngol. 1930;11(1):48-54.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1927, I¹ reported the effects of menthol, camphor and eucalyptol on the vascular state of the mucous membrane. This consisted of acute experiments on clinical patients and laboratory animals, in which an attempt was made to determine the pharmacologic action of these drugs. I reported that menthol, even in dilutions as low as 0.5 per cent, proved irritating to the mucous membrane, causing a swelling rather than a constriction of these tissues as is popularly believed. On the other hand, camphor and eucalyptol in dilutions up to 5 per cent, although irritating to some degree, cause only a mild local reaction when sprayed into the nose. In this article I shall report the actual anatomic changes produced in the nasal mucous membrane of rabbits sprayed daily over a definite period of time. These experiments were designed to parallel the usual application of these drugs in practice. Liquid petrolatum solutions . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Departments of Pharmacology and Anatomy, University of Chicago.

Footnotes
Submitted for publication, Aug. 12, 1929.

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