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Vijay R. Ramakrishnan, MD; Sherif Said, MD, PhD; Todd T. Kingdom, MD

Arch Otolaryngol Head Neck Surg. 2009;135(9):949-952.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Leiomyosarcoma (LMS) is a rare soft-tissue cancer of the head and neck, accounting for 1% to 2% of nasal cavity and paranasal sinus tumors. It is more commonly found in the gastrointestinal or genitourinary tract. Leiomyosarcoma of the head and neck is associated with a history of radiation therapy, retinoblastoma, chemotherapy, human immunodeficiency virus, or AIDS. We describe what we believe is the first case of an LMS of the sphenoid sinus in the English-language literature and include a review of the literature on LMS of the paranasal sinuses, which identified approximately 50 cases of primary sinonasal LMS.

A patient presented with a sphenoid sinus mass and underwent endoscopic surgical treatment. Pathologic examination demonstrated a low-grade LMS. A recommendation was made to pursue adjuvant radiotherapy, which the patient declined. Surgical excision is the mainstay of therapy for low-grade . . . [Full Text of this Article]

REPORT OF A CASE

COMMENT

AUTHOR INFORMATION

Author Affiliations: Departments of Otolaryngology (Drs Ramakrishnan and Kingdom) and Pathology (Dr Said), University of Colorado Denver Health Sciences Center.

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