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Arch Otolaryngol Head Neck Surg. 2009;135(9):947-948.

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Diagnosis: Nasal chondromesenchymal hamartoma (NCMH)

A hamartoma is a tumorlike lesion that results from excessive growth of tissues that are indigenous to the site of origin. Although hamartomas are not unusual in the head and neck region, their occurrence in the nasal cavity is quite rare; NCMH, which is a proliferation of mesenchymal and cartilaginous elements, is one of these rare nasal hamatomas. The pathogenesis of NCMH is poorly understood but is suspected to be an embryologic rest derivative.¹ The lesion may be an upper respiratory tract analogue of a chest wall mesenchymal hamartoma that is found in infants and children.

Consistent with the purported developmental origin of NCMH, the majority of cases have been diagnosed in neonates and infants. The initial 1998 report of NCMH included 7 patients, 6 of whom were 3 months old or younger.² One of the original patients was 7 years old. Eight of the 21 subsequent case reports of . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2009;135(9):945.
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