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Pathology Quiz Case 1: Diagnosis
Arch Otolaryngol Head Neck Surg. 2009;135(8):834.
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Diagnosis: Epithelial-myoepithelial carcinoma (EMC)
Epithelial-myoepithelial carcinoma is a rare low-grade malignant neoplasm of the salivary glands. It accounts for approximately 1% of salivary gland neoplasms and presents at a mean age of 61 years, with a higher incidence in females (1.5-2:1).1-2 The most common primary sites for EMC are the parotid gland (approximately 75%), submandibular glands (10%), and minor salivary glands (10%).1, 3 Less frequently, EMCs have been found in the maxillary sinus, nasal cavity, lacrimal glands, and tracheobronchial tree.4-7 In this case, the tumor ostensibly arose from minor salivary glands located on the laryngeal surface of the epiglottis. To the best of our knowledge, this is the first reported case of epiglottic EMC.
The microscopic features of EMC were first characterized in the 1950s, but for many years, the tumor was reported under disparate names, including adenomyoepithelioma, clear cell adenoma, tubular solid adenoma, monomorphic clear cell tumor, glycogen-rich adenoma, . . . [Full Text of this Article]
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Pathology Quiz Case 1
Jiovani M. Visaya, Eugene A. Chu, John Schmieg, Jeffrey S. Iding, and Wayne M. Koch
Arch Otolaryngol Head Neck Surg. 2009;135(8):832.
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