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A Case Report and Review of the Literature

Yan Peng, MD, PhD; Huan-You Wang, MD, PhD; Kyle H. Molberg, MD

Arch Otolaryngol Head Neck Surg. 2009;135(6):606-610.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is the most common form of chronic leukemia in the United States and Europe.¹ It has been associated with an increased incidence of a second neoplasia, including carcinomas in various parts of the body. For example, in large population-based studies^2-3 of solid tumors in patients with CLL/SLL, markedly increased risks were observed for Kaposi sarcoma, malignant melanoma, and carcinomas of the larynx and the lung. In contrast, occurrence of either synchronous (coexisting) or dyssynchronous (subsequent) poorly differentiated carcinoma and CLL/SLL in the skin is extremely rare. There are, so far, only limited single case reports in the literature.⁴ The case reported herein is another rare example of a cutaneous colocalized invasive poorly differentiated carcinoma and CLL/SLL of the head and neck region.

REPORT OF A CASE

In December 2005, the patient, a 62-year-old man, presented with . . . [Full Text of this Article]

HISTOMORPHOLOGIC CHARACTERISTICS AND IMMUNOHISTOCHEMICAL ANALYSIS

FLOW CYTOMETRY

COMMENT

AUTHOR INFORMATION

Author Affiliations: Department of Pathology, The University of Texas Southwestern Medical Center at Dallas.

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