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Arch Otolaryngol Head Neck Surg. 2009;135(5):522-523.

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Diagnosis: Osteoblastoma

Osteoblastoma, which is a rare benign neoplasm of osteoblastic differentiation, accounts for fewer than 1% of all primary bone tumors.¹ It usually presents in the vertebral column, long bones, and small bones of the hands and feet.^1-2 However, 77 cases arising in the jaws have been reported to date.¹ There is a male predilection, with a male to female ratio of 2:1.^2-5 Osteoblastomas seem to occur predominantly on the left side of the posterior mandible,¹ as in the present case. Most patients (90%) with osteoblastoma are younger than 30 years.^{4, 6}

Histologic examination of the biopsy specimen showed sections of fibrofatty tissue, with a circumscribed lesion that was composed of haphazard anastomosing trabeculae of osteoid, rimmed by plump osteoblasts (Figure 3). Numerous osteoclasts were admixed with the osteoblasts, and the intervening stroma was vascular and contained extravasated red blood cells (Figure 4). The associated lymph node showed . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2009;135(5):521.
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