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Arch Otolaryngol Head Neck Surg. 2009;135(5):522.

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Diagnosis: Glomangiopericytoma (sinonasal-type hemangiopericytoma [HPC])

Hemangiopericytomas are rare mesenchymal neoplasms that were originally thought to arise from the pericytes of Zimmerman, although the true differentiation is unclear. Approximately 15% of all soft-tissue HPCs occur in the head and neck region, where most of them are found within the nose or paranasal sinuses.¹ Because the clinical and histopathologic features of sinonasal-type HPCs, also referred to as HPC-like tumor or sinonasal glomus tumor, differ from those of soft-tissue HPCs found elsewhere in the body, they are considered a distinct entity.² The World Health Organization classification of head and neck tumors in 2005 suggested that sinonasal-type HPCs should be named glomangiopericytomas because of their similarities to glomus tumors.³ Patients with these lesions most often present with nasal obstruction or epistaxis in their seventh decade of life.² Clinically, glomangiopericytomas typically appear as polypoid, beefy-red to grayish pink, soft, fleshy masses within the nasal cavity or paranasal sinuses. They . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2009;135(5):520.
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