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Arch Otolaryngol Head Neck Surg. 2009;135(5):518-519.

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Diagnosis: Bronchogenic cyst

Bronchogenic (or bronchial) cysts are rare congenital anomalies that result from abnormal development of the tracheobronchial tree. At approximately the fourth week of gestation, the respiratory diverticulum forms as an outgrowth of the ventral foregut and then extends inferiorly to form the trachea, bronchi, and lungs. Abnormal budding of the tracheobronchial system can occur, giving rise to supernumerary bronchi if the outgrowth remains in continuity with the developing tree or bronchogenic cysts in cases in which this connection is obliterated. The majority of bronchogenic cysts occur in the anterior mediastinum (83% in one 22-year retrospective case review)¹ or within pulmonary parenchyma. However, extrathoracic bronchial cysts can form as the result of abnormal budding of the proximal trachea^1-2 or from superior migration of unattached buds, which are then pushed anteriorly by the mesenchymal bars that form the sternum.¹ Extrathoracic cysts most commonly occur in the suprasternal notch and manubrium but may . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2009;135(5):517.
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