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Muhammad Shakeel, MRCS; Jonathan R. Newton, MRCS; Charles Sutherland, MRCPath; Bhasker Ram, FRCS

Arch Otolaryngol Head Neck Surg. 2009;135(2):202-204.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Orofacial granulomatosis (OFG) is an uncommon clinical entity, and not much is known about its pathogenesis. It is a disorder of chronic granulomatous inflammation that characteristically presents with labial enlargement and oral ulceration, but a number of other sites in the oral cavity can also be involved.^1-2 The majority of cases of OFG occur in isolation, although a proportion do present in association with established Crohn disease, sarcoidosis, or Melkersson-Rosenthal syndrome.³ There are a number of clinical and histologic similarities between OFG and these conditions, but the exact relationship remains unclear.⁴ We present a case of OFG as the pathologic mechanism in chronic persistent tonsillitis.

REPORT OF A CASE

A 22-year-old white man presented to the maxillofacial surgery unit with a 6-month history of swelling and fissuring of his lower lip. He was otherwise fit and well. Clinical examination revealed a . . . [Full Text of this Article]

COMMENT

AUTHOR INFORMATION

Author Affiliations: Department of Otolaryngology–Head and Neck Surgery, Aberdeen Royal Infirmary, Aberdeen, Scotland.

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