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Arch Otolaryngol Head Neck Surg. 2009;135(10):1059-1060.

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Diagnosis: Rhabdomyoma, adult type

Rhabdomyomas are rare benign tumors with striated muscle cell differentiation that are classified as either cardiac or extracardiac. Cardiac rhabdomyomas are believed to be hamartomatous lesions and are most often found in the hearts of children with tuberous sclerosis.¹ Extracardiac rhabdomyomas are well-differentiated neoplasms that are clinically and morphologically divided into adult, fetal, genital, and rhabdomyomatous hamartoma types.² Adult rhabdomyomas predominantly occur in elderly men (median age, 60 years; male to female ratio, 3:1), and 90% are located in the head and neck.² While adult head and neck rhabdomyomas are usually solitary tumors, 25% of cases are multinodular, with small nests of tumor in adjacent tissue, and 5% are multifocal.³

Adult head and neck rhabdomyomas are tumors of mesenchymal origin, derived from cells of the branchial arches. Therefore, they arise mainly from the oral cavity or the oropharynx, but they can also be found in the submandibular region and the . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2009;135(10):1057.
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