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Arch Otolaryngol Head Neck Surg. 2008;134(6):670.

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Diagnosis: Teflon granuloma of the larynx

Teflon (polytef) was introduced in 1962 to augment the true vocal cord in cases of dysphonia or aspiration. It was the mainstay for treatment of this problem for more than 25 years. However, according to the literature, many problems have developed after the injection of Teflon. Most of the problems appear to result from overinjection, from misplaced injections, or from an overexuberant tissue response by the patient's immune system. Such complications often lead to Teflon granuloma of the larynx, which can cause symptoms ranging from dysphonia to airway obstruction. The possibility of granuloma formation, in addition to the introduction of alternative materials for injection, has led to a decrease in the use of Teflon. However, Teflon injections are still being administered, especially in terminal cases, in which the long-term concern for granuloma formation is diminished. While many other materials have been used for injection . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2008;134(6):669.
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