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Arch Otolaryngol Head Neck Surg. 2008;134(3):331.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Pigmented villonodular synovitis (PVNS) of the temporomandibular joint

The term PVNS was introduced in 1941 by Jaffe et al¹ to describe the histologic characteristic features of the tenosynovial lesion, which included nodules, villi, and pigment. It is an uncommon disease, with an incidence of only 1.8 cases per million per year.² It is nearly always monoarticular. Most often, it involves large joints or extremities, with the knee being the most affected site. Occurrence in the temporomandibular joint is distinctly rare; the first case (to our knowledge) was reported by Lapayowker et al³ in 1973.

The etiology of PVNS remains controversial and unclear. Jaffe and colleagues¹ considered the disease to be of an inflammatory origin. Other possible pathogenetic factors have included intra-articular hemorrhage due to repeated trauma, disturbances in lipid metabolism, and a pathologic immune response.⁴ However, the clinical aggressiveness seen in certain cases has led some authors to regard PVNS as neoplastic in origin. The lesion has been . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2008;134(3):329.
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