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Arch Otolaryngol Head Neck Surg. 2008;134(2):217.

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Diagnosis: Angiolymphoid hyperplasia with eosinophilia (AHE)

Angiolymphoid hyperplasia with eosinophilia, which was first described in the English-language literature by Wells and Whimster¹ in 1969, is a benign vascular lesion that forms nodules in the head and neck. The term epithelioid hemangioma (EH) has also been used to further classify these lesions as benign vascular neoplasms, thereby differentiating them from histiocytoid hemangioma,² which includes all vascular lesions characterized by histiocytoid endothelium, whether benign or malignant.

Angiolymphoid hyperplasia with eosinophilia appears predominantly in the third to fifth decades of life, with a peak incidence occurring during the fourth decade and a male-female ratio of nearly 2:1.^3-4 It typically presents as single or multiple nodules involving the head and neck region, especially the ear, periauricular area, forehead, and scalp; a few lesions can also be found in the extremities.⁴ The lesions involve the subcutaneous tissue (82%), followed by the dermis and the deep soft tissue.⁴ Common symptoms are . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2008;134(2):215.
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