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Eosinophilic Granuloma Manifesting as Painless Cervical Lymphadenopathy in a Patient Positive for Human Immunodeficiency Virus 1
Peggy S. Myung, MD, PhD;
Mondira Kundu, MD, PhD;
Soo Kim Abboud, MD
Arch Otolaryngol Head Neck Surg. 2008;134(2):203-205.
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INTRODUCTION
Eosinophilic granuloma is rarely reported within lymph nodes. Furthermore, it is even more rarely reported in the setting of human immunodeficiency virus (HIV) infection. No definitive etiologic association exists between Langerhans cell histiocytosis (LCH) and HIV. However, their potential relationship underscores the significance of cytokines and their influence on biological niches required for Langerhans development and homeostasis.
REPORT OF A CASE
A 45-year-old man with no remarkable medical history was seen with bilateral nontender cervical lymphadenopathy and a 4.5-kg weight loss during the last 6 months. He had no fever, chills, symptoms of an upper respiratory tract infection, or history of cancer.
Physical examination disclosed a palpable cervical lymphadenopathy that was more marked on the left side than on the right side. In addition, the patient demonstrated bilateral painless parotid enlargement. Results of a nasopharyngeal laryngoscopic examination were unremarkable with the . . . [Full Text of this Article]
COMMENT
AUTHOR INFORMATION
Author Affiliations: Departments of Otorhinolaryngology–Head and Neck Surgery (Drs Myung and Abboud) and Pathology and Laboratory Medicine (Dr Kundu), University of Pennsylvania Health System, Philadelphia.
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