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  Vol. 134 No. 12, December 2008 TABLE OF CONTENTS
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 •Oncology
 •Head & Neck Cancer
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Misleading Report on the Prevention of Major Depression Among Patients With Head and Neck Cancer—Reply

William M. Lydiatt, MD; William J. Burke, MD

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In reply

We thank Coyne for the opportunity to clarify the issues that concern him. Coyne mentions a number of the limitations of our study that we addressed in detail in our article. We concur that this small pilot study is unable to offer any statistical certainty about the outcome of this approach.

We obviously have no control over how our findings have been perceived or reported in the medical or general press. We believe that the positive (and, perhaps in Coyne's case, negative) reactions to our preliminary data are related to the unique approach that we took to the enormous problem of depression in persons with cancer of the head and neck. Depression is very common in these patients (we quoted the literature range of 15%-40%, and we observed in our small study a rate of 50% on 1 measure of . . . [Full Text of this Article]


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