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Pathology Quiz Case: Diagnosis
Arch Otolaryngol Head Neck Surg. 2008;134(11):1234.
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Diagnosis: Cholesterol granuloma (CG) of the left maxillary sinus
Cholesterol granulomas are benign lesions that can develop in various parts of the body, including the breast, testis, and head and neck.1-2 In the head and neck area, the most common site of involvement is the temporal bone, and this site is often associated with chronic otitis media and cholesteatoma. Cholesterol granulomas of the paranasal sinuses are less common. Of the paranasal sinuses, the maxillary sinus is most commonly involved.3 Cholesterol granulomas of the maxillary sinus usually occur in males and are predominantly unilateral.4 The presenting symptoms of maxillary sinus CGs may include nasal obstruction, facial pain, and, rarely, clear, golden-yellow rhinorrhea.5 Cholesterol granulomas are often expansile lesions that can cause bony destruction and compression of adjacent structures. Radiographically, the erosive, expansile features of CGs may be suggestive of malignancy; therefore, biopsies must provide sufficient tissue to definitively rule out malignancy. Because CGs can be morphologically similar to a malignant . . . [Full Text of this Article]
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Pathology Quiz Case
Sachin Parikh, Ingerlisa W. Mattoch, Christina Kong, and Peter H. Hwang
Arch Otolaryngol Head Neck Surg. 2008;134(11):1233.
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