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Differentiating Tonsillitis From Glandular Fever: Is the Lymphocyte–White Blood Cell Count Ratio Any Help?
Emma Louise Smale, BMBCh, MRCSEd;
Stephen Mcdonald, BMBCh, MRCS;
Vikram Dhar, MBBS, MRCS
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We were very interested to read the article by Wolf et al1 titled "Lymphocyte–White Blood Cell Count [L/WCC] Ratio: A Quickly Available Screening Tool to Differentiate Acute Purulent Tonsillitis From Glandular Fever." We agree that a rapidly available and cost-effective screening tool would undoubtedly be useful in the detection of glandular fever. Wolf and coauthors comment that the L/WCC ratio had a sensitivity of 90% and a specificity of 100% for the detection of glandular fever and that the "specificity and sensitivity of this test seem to be better than the mononucleosis spot test itself." However, such a statement is misleading; the group used the Monolatex test (Biokit SA, Barcelona, Spain), one of the commercially available monospot testing kits, as their diagnostic criterion standard. The Monolatex test has a sensitivity of 93.9% and a specificity of 98.3% . . . [Full Text of this Article]
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RELATED LETTER
Differentiating Tonsillitis From Glandular Fever: Is the Lymphocyte–White Blood Cell Count Ratio Any Help?—Reply
Dennis Malcolm Wolf, Ilka Friedrichs, and Abbad G. Toma
Arch Otolaryngol Head Neck Surg. 2007;133(9):952.
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RELATED ARTICLE
Lymphocyte–White Blood Cell Count Ratio: A Quickly Available Screening Tool to Differentiate Acute Purulent Tonsillitis From Glandular Fever
Dennis M. Wolf, Ilka Friedrichs, and Abbad G. Toma
Arch Otolaryngol Head Neck Surg. 2007;133(1):61-64.
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