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Arch Otolaryngol Head Neck Surg. 2007;133(9):949-950.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Salivary duct carcinoma (SDC)

Kleinsasser et al¹ first described SDC in 1968. However, this pathologic entity was largely overlooked until the 1990s. In 1991, the World Health Organization included SDC in their salivary neoplasm classification.² In recent years, numerous clinicopathologic studies have shed new light on this uncommon, high-grade salivary gland malignancy. Salivary duct carcinoma affects a preponderance of men (4:1), usually in the fourth to sixth decades of life. It has been described in both major and minor salivary glands, but more than 80% of cases occur in the parotid gland.^3-4 Patients commonly present with a history of a painless, rapidly enlarging mass, although though 25% to 60% have facial palsy and as many as a third may have associated pain.^3-4 While SDC usually begins de novo, studies suggest that it can arise as a component of carcinoma ex pleomorphic adenoma. This theory is supported by the fact that the most common histologic . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2007;133(9):947.
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