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Arch Otolaryngol Head Neck Surg. 2007;133(6):622-623.

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Diagnosis: Infantile myofibromatosis

Myofibromas are rare fibrous tumors that most commonly affect infants and young children. Typical lesions are firm or rubbery and usually present as a solitary mass or as multiple nodules with or without visceral involvement. Solitary lesions have a predilection for the head and neck (36%) and trunk (33%) and can appear in skin, muscle, subcutaneous tissue, and bone.¹ While individual tumors can present at any age, approximately 50% of solitary lesions are present at birth and more than 75% emerge before 12 months of age.^1-2 There also appears to be a predilection for boys (male-female ratio, 2:1).¹ Despite being rare overall, myofibroma is the most common fibrous tumor of infancy and childhood^2-4 and should therefore be considered in any child with a nodular growth in the head and neck region. Within the head and neck, myofibroma has been documented in the scalp, forehead, orbit, oral cavity, larynx, parotid gland, . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2007;133(6):620.
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