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Arch Otolaryngol Head Neck Surg. 2007;133(4):415.

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Diagnosis: Myxoma of the frontal sinus

Myxomas are uncommon benign, slow-growing, expansile neoplasms of mesenchymal origin. They typically occur in the heart, skeletal muscle, jaw, skin, and lower urogenital tract and generally present in the second and third decades of life.¹ Andrews et al² reviewed 169 cases involving myxomas of the head and neck region. They reported that the most common site of occurrence was the mandible, followed by the maxilla.² Myxomas probably account for fewer than 0.5% of all nasal and paranasal sinus tumors.¹ Moreover, myxoma of the frontal sinus is extremely rare, and, to our knowledge, only 2 other cases have been reported in literature.^3-4

The clinical course of myxomas is characterized by insidious, painless lesions that often remain undetected for several years. When symptoms of nasal congestion, epistaxis, or distortion of the facial architecture start to occur, these tumors are considered to be more advanced. Although myxomas are benign, they are locally invasive . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2007;133(4):412.
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