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Arch Otolaryngol Head Neck Surg. 2007;133(4):409-410.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Schwannoma of the trigeminal nerve in the pterygopalatine fossa

Schwannomas are nerve sheath tumors that originate from Schwann cells. Approximately 25% to 45% of all reported cases occur in the head and neck region, with only a small percentage involving the nose and paranasal sinuses.¹ Schwannomas of the nose and paranasal sinuses arise from intranasal nerves, ophthalmic and maxillary branches of the trigeminal nerve, and branches of the autonomic nervous system. There is no sex or racial predilection, and the tumor commonly presents in the second and fourth decades of life.^2-4

Schwannomas are usually slow growing and benign; however, a malignant variant has been reported.^3-4 Ghosh et al⁵ found that 16 of 115 cases of the malignant variant occurred in the head and neck region. Thirty percent of the cases are associated with von Recklinghausen disease. The association with von Recklinghausen disease is usually indicative of a poor prognosis, with a 5-year survival rate of 30% compared with an . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2007;133(4):407.
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