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  Vol. 133 No. 2, February 2007 TABLE OF CONTENTS
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  •  Online Features
  Clinical Problem Solving: Pathology
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 •Viral Infections
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Pathology Quiz Case 2: Diagnosis

Arch Otolaryngol Head Neck Surg. 2007;133(2):201.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Molluscum contagiosum (MC)

Molluscum contagiosum is a virally induced epithelial hyperplasia caused by the MC virus (MCV), which is a large, double-stranded DNA virus and the most common poxviral pathogen that infects humans.1-2 It replicates and lives in the cytoplasm of the epidermal cells.3 This common benign skin infection primarily affects children. It also affects sexually active adults and some immune-suppressed patient populations.2, 4 However, our patient was an immunocompetent adult. The reason for the predominance of MC in children remains unknown.5

Humans are the only host for MCV, the pathogenesis of which is unclear because it cannot be grown in cell cultures or animal models.2 Molluscum contagiosum virus infections occur worldwide but are most prevalent in warm, moist climates and in populations with imperfect personal hygiene.4 Epidemiologic studies show incidence rates ranging from 2% to 10% of the population.3 The virus is transmitted primarily by skin-to-skin contact,3 by contact with a fomite (eg, . . . [Full Text of this Article]


RELATED ARTICLE

Pathology Quiz Case 2
Seda Turkoglu, Ozcan Cakmak, Sefa Kaya, Aysel Colak, and Beyhan Demirhan
Arch Otolaryngol Head Neck Surg. 2007;133(2):199.
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