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Arch Otolaryngol Head Neck Surg. 2007;133(11):1168.

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Diagnosis: Ameloblastoma, acanthomatous type

Ameloblastomas are benign but locally aggressive epithelial neoplasms that arise from undifferentiated odontogenic tissue. They are relatively uncommon, representing between 1% and 19% of all tumors and cysts in or around the mandible and maxilla.¹ The most common site of origin is the mandibular molar region. Approximately 16% of ameloblastomas are found in the maxilla, with only 2% originating anterior to the premolar area.^1-2 Maxillary ameloblastomas are generally thought to be more aggressive than mandibular ameloblastomas owing to the decreased bone density of the maxilla and the anatomical relationship to vital structures in the orbit and base of the skull.³

Extragnathic sinonasal ameloblastomas are extremely rare. Schafer et al⁴ reported the largest series (to our knowledge), with only 24 cases identified between 1956 and 1996. Compared with gnathic ameloblastomas, which typically present in the third to fifth decades of life, ameloblastomas that are confined to the sinonasal tract usually present . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2007;133(11):1167.
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