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A Case of Tonsil Involvement

B. Thuy Le, MD; Jennifer Setlur, BS; Andrew G. Sikora, MD, PhD; Kelvin C. Lee, MD

Arch Otolaryngol Head Neck Surg. 2006;132:794-796.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Systemic diseases often have varied otolaryngologic manifestations. Mycosis fungoides is a T-cell lymphoma that is often limited to cutaneous involvement but has occasional systemic spread. Careful physical examination and appropriate laboratory studies are keys to establish the diagnosis. We present a case of this unusual entity involving the oropharynx.

REPORT OF A CASE

A 36-year-old man with a 4-year history of mycosis fungoides stage IIB presented to the otolaryngology clinic in January 2005 with a 1-month history of throat pain. He had initially presented with cutaneous lesions in June 2000, and immunohistochemical analysis of a skin shave biopsy specimen obtained at that time confirmed a diagnosis of mycosis fungoides with CD4⁺, CD8^– cell markers. He was treated with a 3-month regimen of bexarotene (Targretin) and interferon, which resulted in hyperlipidemia and hypothyroidism. The cutaneous lesions persisted, and . . . [Full Text of this Article]

COMMENT

AUTHOR INFORMATION

Author Affiliations: Departments of Otolaryngology–Head and Neck Surgery, New York University School of Medicine, New York, NY (Drs Le and Lee and Ms Setlur), and The University of Texas M. D. Anderson Cancer Center, Houston (Dr Sikora).