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Pathology Quiz Case 1: Diagnosis
Arch Otolaryngol Head Neck Surg. 2006;132:556.
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Diagnosis: Epithelial-myoepithelial carcinoma (EMC)
Epithelial-myoepithelial carcinoma, a rare malignant tumor of the salivary glands, was first described in 19721 and was established as a distinct diagnostic entity by the World Health Organization in 1991.2 Before its metastatic potential was realized in studies with sufficient long-term follow-up, EMC was reported under a variety of names, including glycogen-rich adenoma, clear cell adenoma, adenomyoepithelioma, tubular solid adenoma, and salivary duct carcinoma.3 Furthermore, it is difficult to assess the incidence of EMC because it was not included as a specific entity until recently. Current evaluations demonstrate that EMC represents approximately 1% of all salivary gland neoplasms, occurs predominantly in the parotid gland (70%-80%), has a predilection for females, and has a peak incidence in the seventh and eighth decades of life (mean age at onset, 60 years).2-5 However, the youngest patient in the case files of the Armed Forces Institute of Pathology is 15 years old, and EMC . . . [Full Text of this Article]
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Pathology Quiz Case 1
Shane Zim, Jennifer Lee, and Deborah Schofield
Arch Otolaryngol Head Neck Surg. 2006;132(5):554.
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