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Arch Otolaryngol Head Neck Surg. 2006;132:345-346.

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Diagnosis: Glomus jugulare tumor

The definition and classification of glomus tumors of the head and neck have evolved since 1762, when they were described as a mass at the carotid bifurcation that had a glomuslike structure. In 1950, Mulligan¹ called this type of neoplasm a chemodectoma to better reflect its derivation from neural crest cells and chemoreceptor cells. Because of the ability of these cells to produce catecholamines, chemodectomas can be described as chromaffin or nonchromaffin positive. In 1974, the glomus tumor was renamed paraganglionoma based on its anatomical and physiological characteristics. Current terminology of these tumors is often mixed, with glomus tumor being the most common designation in the literature.²

Glomus tumors of the head and neck consist of cells that are normally part of the extra-adrenal neuroendocrine system. The largest concentration of paraganglionic cells is found within the adrenal medulla; however, small patches of paraganglionic cells can be widely dispersed throughout the . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2006;132(3):343.
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