 |
|
Radiology Quiz Case 1: Diagnosis
Arch Otolaryngol Head Neck Surg. 2006;132:344-345.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
Diagnosis: Catecholamine-secreting olfactory neuroblastoma (OFN)
Olfactory neuroblastoma is an uncommon malignant tumor of the nasal cavity that was first described in 1924.1 Since then, fewer than 1000 cases have been reported.1-2 Although many retrospective series have been published describing the clinical management of OFN, hormone-secreting tumors are distinctly unusual.3-4 Especially rare are catecholamine-producing OFNs; to our knowledge, only 2 clinically inactive cases have been reported via immunohistochemical and molecular analysis.5-6 The present case, involving a clinically active catecholamine-secreting OFN, appears to be unique.
Olfactory neuroblastomas are thought to arise from the basal cells of the olfactory epithelium, which are located in the cribriform plate, superior and middle turbinates, and nasal septum.7 They represent 3% to 5% of all malignant tumors of the nasal cavity, show an equal sex distribution, and demonstrate a bimodal peak occurrence in the second and sixth decades of life.8 Patients often present with symptoms of nasal obstruction, epistaxis, and headaches.9 The . . . [Full Text of this Article]
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLE
Radiology Quiz Case 1
Vishad Nabili, Maie St. John, Pejman Cohan, Robert Lufkin, Sunita Bhuta, and Elliot Abemayor
Arch Otolaryngol Head Neck Surg. 2006;132(3):342.
EXTRACT
| FULL TEXT
|
